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T2D is the most significant predictor of adverse outcomes, and it was not accounted for in that modeling study [42]

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Chronic hyperglycemia has been associated with tissue damage and systemic inflammation, both of which can worsen osteoarthritis symptoms over time

10.1038/s41419-018-1291-5 230 XiangL.XieG.LiuC.ZhouJ.ChenJ.YuS.et al (2013)

Rather than eliminating fat entirely, which would be nutritionally inadequate, focus on distributing fat intake evenly throughout the day in moderate amounts