The weight-adjusted approach matters more for peptides with narrow therapeutic windows or those where body composition significantly affects distribution
The topical route is the format with the strongest human clinical trial evidence for skin outcomes, from the landmark 1998 Abdulghani study that outperformed both vitamin C and tretinoin to the Finkley skin-thickness data
Deep static lines require longer protocols and additional modalities
That said, GHK-Cu is not a standalone hair loss treatment
Users who have tried minoxidil without satisfactory results represent another good candidate population
Detcheverry, F., Senthil, S., Narayanan, S., & Badhwar, A