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This drug may also cause side effects, including nausea/vomiting, diarrhea, constipation, headache and dyspepsia

FIGURE 1 Intragastric administration of GRP (172 mg/kg body weight) to germ-free and human microbiota-associated (HMA) mice led to the excretion of approximately 30% unchanged GRP in the urine of both germ-free and HMA mice ( Figure 2 schematically demonstrates the metabolism of GRP and its biologically active derivative SFN within the GIT

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These risks highlight the importance of obtaining GLP-1 receptor agonists only through legitimate medical channels with proper prescriptions and oversight

5a), as this model has been thoroughly characterized 19,20