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NPJ Precision Oncol

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Methods PROM response rates are calculated as the percentage of completed PROMs relative to those sent

If suspected, it is appropriate to manage with broad-spectrum antibiotics, such as metronidazole (10 to 15 mg/kg, every 12 hours, PO) or amoxicillin (10 mg/kg, every 12 hours, PO) for an extended duration such as 21 to 28 days

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Activation of myofibroblasts, which produce ECM as effector cells in fibrotic illnesses, is a notable feature of these conditions (Wynn and Ramalingam, 2012