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GHK-Cus copper binding affinity (pK = 16.44) is approximately 10 million times stronger than other tripeptides and comparable to albumins binding strength

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Emphysema (mouse model): Intraperitoneal GHK-Cu attenuated cigarette-smoke-induced emphysema and reduced inflammatory cytokines across the same dose range (PMID 35936787)

Allergic reactions: Although rare, rash or allergic-type reactions have been noted in some cases

However, its clinical utility is limited due to rapid enzymatic breakdown

Infused with squalane, rice ceramide, panthenol, and allantoin, it provides lasting comfort and smooths away rough, flaky patches without heaviness