Lima FB, Machado UF, Bartol I, et al
- Enhance your skin, by providing vitamin A, vitamin C, and vitamin E that can stimulate collagen production and protect your skin from oxidative damage and inflammation
CYP1A1 metabolism of estrogen, polyaromatic hydrocarbons, and more CYP1A2 metabolism of caffeine, duloxetine, bupropion, aflatoxin B, and more CYP2A6 metabolism of nicotine, coumarin, and more CYP2B6 metabolism of ketamine, methadone, sertraline, and more CYP2C9 metabolism of warfarin, rosuvastatin, celecoxib, and more CYP2C19 metabolism of clopidogrel, some proton pump inhibitors, more CYP2D6 metabolism of some antidepressants, antipsychotics, more CYP3A4 metabolism of half of all prescription drugs CYP2E1 metabolism of fatty acids, alcohol, and some anesthetics Phase II detoxification genes: UGT, GST, Nrf2 Phase II detoxification involves taking the metabolites of phase I and modifying them to be easily excreted through conjugation with sulfur, glutathione, glucuronic acid, amino acids, or methyl groups
Additionally, vitamin C functions as an antioxidant
Combining detan and bleach treatments is not recommended because they can overwhelm the skin barrier
However, in the kidney tissue, which expresses high levels of NRK1, the effects of NR and NRH are comparable 125,128
