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IL-1, which is secreted by macrophages and has a vital role in psoriasis immunity [22], and IL-6, which activates the JAK-STAT pathway and exhibits elevated levels in psoriasis patients lesions [23], were both significantly increased in psoriasis-induced mice

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Vascular smooth muscle cells migrate into the intima and proliferate, leading to fibrous cap formation, plaque destabilization and rupture, ultimately culminating in thrombosis and contributing to acute coronary syndrome 14

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They are non-enveloped, single-stranded RNA viruses with small 7.5 kilobase genomes encoding 11 proteins (135)