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If you increase your dose to get results, you are also increasing your exposure to potentially impure substances
They added GHK-Cu in concentrations of 10 M to 10 M and measured: Collagen synthesis (by radioactive proline incorporation) Non-collagen protein synthesis Cell proliferation What they found: Stimulation of collagen synthesis by 70 % at the optimal concentration of 10 M (1 nM) The effect was NOT dependent on increased proliferation, fibroblasts increased production per cell Background: GHK without copper had a dramatically weaker effect , Cu is critical Reversibility: After removing GHK-Cu, synthesis returned to baseline Why it matters: This is the fundamental mechanistic study that documented the effect of GHK-Cu on collagen
Similar content being viewed by others Background Malignant melanoma is a rare tumor during childhood and accounts for up to 0.9% of all pediatric malignancies [1, 2]
The release of acidic metabolites such as lactate, generated by tumor cells via glycolysis, exacerbates local acidosis within the TME (90)
