Lilly is studying retatrutide in several Phase 3 clinical trials to evaluate its potential efficacy and safety in obesity and overweight with at least one weight-related medical problem, type 2 diabetes, knee osteoarthritis, moderate-to-severe obstructive sleep apnea, chronic low back pain, cardiovascular and renal outcomes and metabolic dysfunction-associated steatotic liver disease
Dysregulation of GLP-1R signaling contributes to impaired insulin secretion, altered lipid homeostasis, hyperglycemia, and metabolic dysfunction observed in obesity and type 2 diabetes [1]
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Over time, though, patients began sharing stories of serious side effects that were not widely discussed
After reconstitution, the vial goes straight into the refrigerator
Alternative medications to retatrutide If your doctor recommends an alternative treatment to retatrutide, they may suggest other medications from different drug classes to manage or promote weight loss