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Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor

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Increased the mRNA levels of pro-inflammatory cytokines, tumour necrosis factor partially and reduced anti-inflammatory IL-4/13A, IL-10, IL-11 and TGF-1 mRNA levels partially in association with target of rapamycin (TOR) signaling

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While primarily studied for its roles in autoimmune conditions, PEPITEM influence on immune cell behavior has implications for bone healing because the inflammatory phase of fracture repair depends heavily on coordinated immune cell activity

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Hemodynamic and histological effects of traumatic brain injury in eNOS-deficient mice

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