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D- as well as L-methionine were found to be equally effective, suggesting that depletion of sulfur was at the root of the primary defect and that it was unrelated to protein synthesis

POTENTIAL MECHANISMS UNDERLYING THE DECLINE IN GH SECRETION WITH AGE Three hypothalamic factors regulate GH secretion: somatostatin (Somatotropin Release-Inhibiting Factor, SRIF), growth hormone-releasing hormone (GHRH), and ghrelin (11) (Figure 2)

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