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Peptide therapeutics position statement

Originally isolated for its gastroprotective properties, research has expanded to investigate its potential effects on tissue repair, angiogenesis, and anti-inflammatory pathways

Biased agonism of endogenous opioid peptides at the -opioid receptor

Vitamin B12 is key to nerve health

Endocrinology 149:574579 Bjerre Knudsen L, Madsen LW, Andersen S, Almholt K, de Boer AS, Drucker DJ, Gotfredsen C, Egerod FL, Hegelund AC, Jacobsen H, Jacobsen SD, Moses AC, Molck AM, Nielsen HS, Nowak J, Solberg H, Thi TD, Zdravkovic M, Moerch U (2010) Glucagon-like Peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation

This early response typically occurs in people with higher baseline GLP-1 sensitivity or those starting at slightly higher initial doses