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34 The indicators are categorized based on whether they involve avoiding the initiation of a PIM or discontinuing one that is already prescribed

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Ser286 performs the same nucleophilic attack on DON, but then releases diazo groups and leads to the formation of enzyme-inhibitor complexes (Thangavelu et al., 2014)

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Monitoring focuses on glucose handling, IGF-axis context, cardiovascular risk, and symptoms that may suggest excessive pathway activity