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Treatment Satisfaction Overall, 83% of respondents ( n = 457) reported that they were satisfied with their weight management treatment (Fig

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Disclosures: Rohit Loomba, MD, is a consultant or advisory board member for Aardvark Therapeutics, Altimmune, Anylam/Regeneron, Amgen, Arrowhead Pharmaceuticals, AstraZeneca, Bristol-Myer Squibb, CohBar, Eli Lilly, Galmed, Gilead, Glympse bio, Hightide, Inipharma, Intercept, Inventiva, Ionis, Janssen Inc., Madrigal, Metacrine, Inc., NGM Biopharmaceuticals, Novartis, Novo Nordisk, Merck, Pfizer, Sagimet, Theratechnologies, 89 bio, Terns Pharmaceuticals and Viking Therapeutics

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Furthermore, pyocyanin has been found to disrupt CFTR Cl - transport by inhibiting the endocytic recycling of CFTR and inactivating the airway epithelial vacuolar ATPase, which reduces the expression and trafficking of CFTR, hence disrupting Cl - transport (175, 176)