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Another positive finding was seen in 60 patients with BED and T2DM when dulaglutide, which is not currently licensed for obesity, was compared with placebo at 12 weeks 222

People already dealing with bloating from GLP-1 medications should approach this supplement with particular caution, as the effects can stack

This is why patients are paying attention

Broad Therapeutic Effects : Tirzepatide results in clinically significant improvements in multiple obesity-related complications, including sleep apnea, metabolic dysfunction-associated steatohepatitis, heart failure with preserved ejection fraction, and diabetes prevention [79]

15,392 In Wistar rats, a diet high in fat was found to lead to a decrease in the ratio of OPG/RANKL, which resulted in increased bone resorption and ultimately a reduction in bone mass

Whether that specificity translates to superior clinical outcomes remains to be proven through rigorous trials