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The ongoing degradation of NRF2 ensures that only the basal expression levels of NRF2 target genes are maintained, supporting essential housekeeping functions

These findings suggest that ove-ECM1-MenSCs facilitated a consistent and sustained expression of ECM1 at the site of liver injury and exerted stronger antifibrotic effect through inhibiting HSC activation than unmodified MenSCs

It has been demonstrated that the Na+ dependent uptake of other nutrients into skeletal muscle is increased by insulin, for example amino acids (Zorzano et al