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Several studies have reported that genetic and structural abnormalities of mitochondria are associated with various psychiatric diseases.103104 In particular, psychosis and cognitive deterioration are common features of mitochondrial diseases such as mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome.105 Mitochondrial metabolism is also important for producing ROS

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doi: 10.3389/fimmu.2023.1129323 138 ZahaviDWeinerL

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