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The effects of glucagon-like peptide-1 receptor agonists on adipose tissues in patients with type 2 diabetes: a meta-analysis of randomised controlled trials

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LIRA a dosis de 1,8mg diarios induce mejora de la enfermedad esteatsica heptica asociada a disfuncin metablica (MASLD) con resolucin de esteatohepatitis en el 39% de los casos, mientras que la fibrosis progres en el 9% de los pacientes, frente al 36% tratados con placebo29 (fig

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It targets melanin production, which reduces the appearance of dark spots, age spots, and uneven skin tone

Mechanistically, at very low, non-toxic concentrations, the peptide stimulates collagen, glycosaminoglycans, and proteoglycans such as decorin, while modulating the matrix metalloproteinases involved in extracellular matrix remodeling during healing