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The affinity, cAMP activity, and insulinotropic activity in vitro all decline when Ala 8 is substituted with Gly 8 (IC 50 : 44.9 nM220 nM;EC 50 : 0.15 nM1.11 nM)

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3 Results 3.1 Base-case analysis Table 1 summarizes the main findings of a 40-year simulation using the UKPDS model

Krieger, J