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GHK treatment reduces the IGF-dependent secretion of the fibrogenic growth factor (TGF-1) [19], aiding in the resolution of persistent fibrosis and scarring

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Fletcher and colleagues (J Pharmacol Exp Ther, 2021) profiled it across 25 endpoints against selective and non-selective comparators including pramlintide and salmon calcitonin, and cryo-EM structures of cagrilintide bound to CTR and the amylin receptors were reported by Cao and colleagues (Nat Commun, 2025)

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