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10.19045/bspab.2012.11002 40 IheshiulorO.EsonuB

Mice heterozygous for a disrupted UA oxidase transgene (UO X +/) exhibited diminished brain damage and enhanced functional recovery following ischemic stroke, prompted researchers to explore the potential role of UA treatment in animal stroke models [145]

[18] While higher levels of homocysteine have been associated with numerous health complications, levels of homocysteine that are too low can also be problematic and have been associated with peripheral neuropathy (often felt as hand and arm tingling) and an impaired ability to make glutathione, an important antioxidant that reduces inflammation in the body

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PMID 20727946