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Here, the levels of pS6K, a downstream target of mTORC1, were significantly higher in DKD group than in CON group, and the elevated pS6K levels were significantly inhibited after HU treatment (Figures 7A, B)

161 , 19681971, doi: 10.1164/ajrccm.161.6.9907112 (2000)

Long-acting GLP-1RAs: An overview of efficacy, safety, and their role in type 2 diabetes management

Data in (b,c) were analyzed by 1-way ANOVA with Bonferroni multiple comparison test

Some research protocols account for this by using comparatively lower dosing ranges in female study cohorts, reflecting a generally increased sensitivity to IGF-1 receptor activation a pattern also documented in broader growth hormone axis research, not unique to IGF-1 LR3 specifically

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