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While both are effective GLP-1 drugs, one stands out as a clear winner when it comes to faster and more effective weight loss results

Healthcare providers say the drugs can help, but they are not a replacement for long-term lifestyle changes

Exendin-4, a GLP-1R agonist, also suppressed basal expression of several inflammatory mediators and in combination with phosphodiesterase inhibitors, decreased CXCL10 expression by IFN- (a type II-interferon) in human islets and in MIN6 cells (a mouse -cell line)

Delayed gastric emptying: Semaglutide slows the movement of food from the stomach to the small intestine, which helps reduce postprandial (after meal) blood sugar spikes

GLP-1 medications do not replace your DMARD or your biologic

In addition, a large proportion of the GLP-1 RA group (13.8%) had received DPP-4is before baseline, whereas only 0.8% of the DPP-4i group had received GLP-1 RAs prior