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Post-mortem tissue and plasma collection At the completion of behavioral testing, all rats were deeply anesthetized with a cocktail of ketamine (90 mg/kg), xylazine (2.7 mg/kg) and acepromazine (0.64 mg/kg) and decapitated

39 One of the more important aspects of this disease is the chronic inflammatory and oxidative stresses that accompany the infection, which eventually contribute to the loss of CD4 (helper) T-cells, increased opportunistic infections, immuno-deficiency in general, wasting disease, and death

All data were entered into Excel spreadsheets and subsequently subjected to relevant statistical analyses (Graph Pad Prism software)

doi: 10.1186/1740-2557-2-5 517 MaesMMihaylovaILeunisJC

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