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However, if you take additional diabetes medications (metformin, sulfonylureas, or insulin), the combined glucose-lowering effect of berberine plus semaglutide may require dose reductions in your other medications

Efficacy and safety of insulin glargine/lixisenatide fixed-ratio combination (iGlarLixi 1:1) in Japanese patients with type 2 diabetes mellitus inadequately controlled on oral antidiabetic drugs: A randomized, 26-week, open-label, multicentre study: The LixiLan JP-O2 randomized clinical trial

Keep a brief log of energy, appetite, mood, and any physical symptoms for the first 46 weeks

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It can be mixed with water, juice, squash or anything else you prefer