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RNA-Seq Reveals the Circular RNA and miRNA Expression Profile of Peripheral Blood Mononuclear Cells in Patients With Rheumatoid Arthritis

The Evidence: Most of the research has been conducted in animal studies or small pilot human trials with mixed results

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Additionally, Tirzepatide has been found to lower fasting blood glucose levels & increase weight loss in participants who were overweight or obese at the start of clinical trials

It also suppressed pro-inflammatory cytokines (e.g., TNF-, IL-6, IL-8, interferon (IFN)-, IL-12p40, IL-1 and IL-17) and enhanced apoptosis-regulating proteins (caspase-8, Bax), highlighting its potential for managing intestinal inflammation

Jonathan Reed, Lead Researcher of the study