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The 4- and 8-mg doses of glimepiride were more effective than the 1-mg dose

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In contrast, under conditions of nutrient deprivation, oxidative stress, and lysosomal dysfunction, inhibition of mTOR activity and concurrent activation of calcineurin triggers TFEB dephosphorylation (Medina et al., 2015

doi: 10.1152/ajplung.1999.276.2.L289

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