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All peptides were synthesized on a 0.10.4 mmol scale with a Biotage Initiator+ Alstra automated microwave-assisted peptide synthesizer using H-Rink Amide ChemMatrix resin (0.45 meq/g loading)

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given the known effects of GLP-1RAs on GFAP in the models of DR, it is plausible for a direct effect of GLP-1RAs on Mller cells activation in the context of glaucoma