Outline known safety data and tolerability of GHK-Cu in humans Clinical reports note mild local reactions for topical application and rare systemic adverse events at low doses
Some studies have used doses as high as 4,500 mg per day without serious adverse effects
Experimental procedure of HFD-induced obese mice 810 week-old male C57BL/6J mice were purchased from the animal facility of the Faculty of Health Sciences, University of Macau
Jwk K, Gan Y-H
N Engl J Med 387(3):205216 Jastreboff AM, le Roux CW, Stefanski A, Aronne LJ, Halpern B, Wharton S, Wilding JPH, Perreault L, Zhang S, Battula R, Bunck MC, Ahmad NN, Jouravskaya I (2025) SURMOUNT-1 investigators
doi: 10.1007/978-1-4939-2938-2_9