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Recommended needle size and maximum dose volumes of administration in mice.[4, 7, 8] Further Reading and Useful Links Restraining techniques: Maccholz E, et al

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J Biol Chem (1998) 273(42):2710410

As E2 and E3 mice are known to have increased longevity relative to E4 mice (Shinohara et al., 2020), this overall increase in cerebrovascular acylcarnitines could represent compensatory changes to supplement energetics with age, or act as a FA detoxification mechanism, a response which appears blunted in E4s