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The primary measure of effectiveness was the change in glycated hemoglobin A1c (HbA1c) levels, a marker of blood glucose control, from the start of the study to the end of the 26-week period

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For example, research suggests that berberine may positively impact gut bacteria that produce short-chain fatty acids (SCFAs) such as butyrate, which help regulate inflammation, and bile acids, which help regulate cholesterol and triglyceride levels

In skincare, they are studied for their ability to