Injectable GLP-1 medications generally produce greater average weight reductionlargely because subcutaneous delivery ensures a consistent therapeutic dose
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The volumetric finding is a hypothesis worth testing in a powered trial with volume change as a prespecified endpoint, not a demonstration that the drug protects brain tissue
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Improved Body Mass Index (BMI): Semaglutide has been shown to significantly reduce BMI, a measure of body fat based on height and weight