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Histamine can increase intestinal permeability (leaky gut), leading to bloating, cramping, and digestive distress, such as by causing fluctuating diarrhea and constipation, gas, abdominal pain, and discomfort after eating high-histamine foods

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Ipamorelin, the first selective growth hormone secretagogue, stimulates the natural release of growth hormone from the anterior pituitary gland, without unwanted side effects like increased hunger or cortisol spikes, making it ideal for lean muscle mass development and recovery

Current basic research in pharmacology is mostly devoted to the effects of pathways activated by specific drugs, but the role played by drugs in the human microbiome is multifaceted

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doi: 10.3390/ijms19092722 29