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The substrates and products of the DHODH reaction have opposite effects on ferroptosis, suggesting that the potential role of DHODH in regulating ferroptosis sensitivity is independent of its function of producing pyrimidine nucleotides

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Mean age was 64 years, mean BMI 27 kg/m 2 , mean HbA1c 7.4% (57 mmol/mol) and mean fasting glucose 8.5 mmol/l before the study

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