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In one of those studies, 97.5% of 1.3 million patients had at least one comorbidity in addition to T2DM [11]

Fluoroquinolones require monitoring for both hypoglycemia and hyperglycemia, particularly in patients with diabetes, as noted in an FDA Drug Safety Communication

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Certain classical ASMs (e.g., phenobarbital, benzodiazepines, topiramate, vigabatrin) primarily act by broadly suppressing neuronal excitability or markedly enhancing gamma-aminobutyric acid (GABA) receptor activity