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Participants took either Rybelsus or a placebo for two years

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This interaction was also observed in OCT1 29 , and we note R282 is a part of a PESPR motif conserved in OCTs and OATs and found in glucose transporters 54

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10.1371/journal.pone.0130546 114 SuM.ZhaoW.JiangH.ZhaoY.LiaoZ.LiuZ.et al (2025)