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Growth hormone stimulates hepatic IGF-1 production by binding to growth hormone receptors on liver cells, triggering intracellular signaling through the JAK2/STAT5 pathway that upregulates IGF-1 gene expression

For some, Zepbound (tirzepatide), which targets dual hormones, may be recommended for enhanced weight loss

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Your healthcare provider should monitor symptom severity and adjust dosing schedules to minimize discomfort while maintaining therapeutic benefit