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Amylin itself is a hormone co-secreted with insulin by the pancreas, and it plays a natural role in slowing digestion, controlling appetite, and regulating blood sugar levels

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Molecules (Basel, Switzerland) , 19 (11), 1906619077

Perturbations in the gut microbiome (e.g., the imbalance between harmful and protective bacteria) or dysbiosis characterised by, for instance, reduced diversity of short-chain fatty acids (SCFAs) producers and enriched proinflammatory microbes (e.g., H 2 S producers) is said to be responsible for the pathogenesis of IBD, and it is reviewed elsewhere (Kaur et al., 2011