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Hitting it with a high-pressure stream of water creates mechanical stress that can denature the peptide

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10.1128/MCB.25.7.2795-2807.2005 53 El FatimyR.LiS.ChenZ.MushannenT.GongalaS.WeiZ.et al

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Some combinations trigger serotonergic excess at clinically standard doses due to individual receptor sensitivity variability

However, as the field is evolving, some newly uncovered SRs remain unclassified while others are classified as noncanonical SRs, or proteins that simply exhibit scavenger receptor activity (12)