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Some persons have reported serious adverse effects from the increasing usage of GLP-1 medications and comparable pharmaceuticals to treat type 2 diabetes and, in some circumstances, obesity

Gene variants on genes such as MTHFR encoding methylenetetrahydrofolate reductase, MTR encoding methionine synthase, MTRR encoding methionine synthase reductase and CBS encoding cystathionine-B synthase in the methylation pathway can lead to a decreased ability to create sufficient methyl donor (SAMe) and may lead to disruptions in the SAMe:SAH ratio, thus altering methylation capacity and epigenetic regulation

As menopause approaches, these symptoms can progressively worsen

Some worry about GLP-1 weight regain if treatment stops, which can add hidden costs later

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The shiitake mushroom, which offers 37% RDV pantothenic acid for every 100 grams of mushroom, is the star of this group