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This modification enables NFAT translocation into the nucleus, where it regulates the transcription of target genes involved in cardiac remodeling and hypertrophy (189, 190)

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However, the capacity of muscle utilization surpasses its normal production

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Among these, glucagon-like peptide-1 (GLP-1) receptor agonists, which are already approved for weight management and type 2 diabetes, have shown promise

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