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Targeting HSPs in autoimmune diseases HSP90 inhibition and inflammatory control HSP90 inhibitors have shown notable immunomodulatory activity in preclinical autoimmune models, consistent with the role of HSP90 in stabilizing signaling proteins that amplify immune activation

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Cagrilintide is the long-acting amylin analog that Novo Nordisk pairs with semaglutide in CagriSema the combination that produced up to 22.7% weight loss in the REDEFINE-1 Phase 3 trial

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