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While hyperinflammation due to proinflammatory cytokine overproduction has been frequently documented, it is recently recognized that the immune response is markedly suppressed in some cases by the expansion and activity of MDSCs (myeloid-derived suppressor cells) and FoxP3 + Tregs (regulatory T cells)

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Furthermore, results from a phase II clinical trial conducted on AD patients demonstrated that NR administration was associated with favorable alterations in cerebrospinal fluid biomarkers indicative of improved mitochondrial function [23]

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Astaxanthin may increase your immune function, so use caution when taking it if you: Have autoimmune problems Are taking drugs to suppress your immune system Also, be cautious using astaxanthin if you have: Low calcium Low blood pressure Osteoporosis A problem with your parathyroid glands Hormone problems Can astaxanthin interact with medications

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