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Nedelcu RI, Balaban M, Turcu G, Brinzea A, Ion DA, Antohe M, Hodorogea A, Calinescu A, Badarau AI, Popp CG, Cioplea M, Nichita L, Popescu S, Diaconu C, Bleotu C, Pirici D, Popescu R, Popescu CM, Zurac SA (2019) Efficacy of methotrexate as anti-inflammatory and anti-proliferative drug in dermatology: three case reports
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In addition, SARS-CoV-2 ORF3a promotes NRF2 degradation through the recruitment of Keap1, thus weakening the resistance of cells to oxidative stress and promoting ferroptosis [131]
Glutathione mitigates this by decreasing oxidation and boosting natural killer cytotoxicity doubling natural killer (NK) cells according to the previously mentioned study
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