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Davies reports personal fees and grants from Boehringer Ingelheim, Janssen, Novo Nordisk and Sanofi and personal fees from AstraZeneca, Eli Lilly, Gilead Sciences Ltd., Intarcia/Servier, Merck Sharp & Dohme, Mitsubishi Tanabe Pharma Corporation and Takeda Pharmaceuticals International Inc

Moreover, ALS is often further characterized by dysregulated proteostasis and autophagy, which can cause an excess of unfolded proteins, including stress granules, and TDP-43 pathologies

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