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A 2019 systematic review (87) identified three placebo-controlled interventions that examined the effect of oral supplementation with acetyl-L-carnitine (ALCAR

They target melanin through slightly different mechanisms, so combining them can enhance results without significantly increasing irritation

During IV therapy, a small needle inserts a catheter into a vein, injecting the customized IV solution directly into the bloodstream

Laser therapy or chemical peels Laser therapy and chemical peels are advanced options used in skin whitening treatment to reduce pigmentation and improve skin tone

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Additionally, several important enzymes work as markers of OS, including glutathione peroxidase [60], catalase (CAT) [61], superoxide dismutase (SOD) [62], and glutathione-S-transferase (GST) [63]