It helps support antioxidant recycling, detoxification pathways, immune function, mitochondrial health, and cellular repair
Two key nutrients, fibre and protein, play a significant role in stimulating its production
In the trial mentioned above, one year after stopping the GLP-1 medication, participants also saw: Blood pressure levels go back up C-reactive protein levels (an indicator of inflammation) increase VLDL cholesterol (a type that leads to hardened arteries) goes up Triglycerides (a type of blood fat) go up Hemoglobin A1c increases (meaning the level of sugar in the blood) At high levels, these health markers are associated with conditions like type 2 diabetes, obesity, hypertension, and heart disease, to list a few
The weight loss was accompanied by a decrease in food intake in comparison to mice treated with GLP-1 or MK-801 monotherapy or vehicle (Fig
Future integrative studies combining multi-omics profiling, high-resolution plaque imaging, and long-term cardiovascular outcome assessment will be essential to determine whether GLP-1RAs can directly modify plaque biology and improve clinical outcomes
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