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The glucagon component may also contribute to reduced hepatic lipid accumulation, which improves hepatic insulin sensitivity over time

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Research suggests that 5-10% weight reduction can restore menstrual regularity and ovulation in women with PCOS and obesity, though individual variation is significant

Reported VAS ratings were similar for traders versus nontraders for untreated PWS (38.64 vs 38.95, P = 0.89) and PWS with controlled obesity (57.36 vs 55.14, P = 0.35) but varied for PWS with controlled obesity and hyperphagia (70.70 vs 64.46, P = 0.02)