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Compared to stronger actives like retinol, GHK-Cu is generally well-tolerated, making it suitable for a wider range of skin types

ADA selectively activates retinoic acid receptors (RAR-/), thereby inhibiting excessive proliferation and differentiation of keratinocytes, reducing follicular hyperkeratinization, and downregulating inflammatory cytokines such as IL-6, ultimately contributing to its therapeutic effects in acne (Waugh et al., 2004)

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NaBPC157 (10 g or 10 ng/kg i.p.) has a prophylactic effect (applied either 1 hour before, or simultaneously with 96% ethanol (1 ml/rat, i.g.)) and a salutary effect (applied 1 hour after ethanol at the maximum of the lesion's development)

Their concerns are not small ones