Zhang, Hua
Stage 5: Progression to Other Autoimmune Disorders Having Hashimotos puts a person at greater risk for developing other autoimmune conditions like celiac disease, psoriasis, Sjogrens, rheumatoid arthritis, lupus, multiple sclerosis, and many others (12-14) This is a progression of the autoimmune response as the immune system continues to be imbalanced, it may find additional glands and body tissues to attack, such as the small intestine in celiac disease, the saliva and tear glands in Sjogrens, and the joints in rheumatoid arthritis
Increase of fat oxidation and weight loss in obese mice by a fragment of human growth hormone
Mingrone, AV
Sensitive skin Challenges: Retinol causes more irritation Even gentle peptides may sting on compromised barrier Strategy: Start with low-dose retinol (0.25% or 0.3%) Use soothing peptides (Matrixyl, copper peptides) Apply retinol 2-3x weekly initially Use sandwich method (moisturizer retinol peptides moisturizer) Consider separate AM/PM application Dry skin Challenges: Retinol increases dryness Needs extra hydration Strategy: Use hydrating peptide serums with hyaluronic acid Apply retinol over damp skin Heavy moisturizer after peptides + retinol Consider retinol in emollient base (like squalane) Oily/acne-prone skin Advantages: Tolerates retinol well (less dryness) Retinol helps with breakouts Strategy: Can use higher retinol concentrations (0.5-1%) Lighter peptide serums (water-based, not oil-heavy) Oil-free moisturizer Can apply peptides + retinol nightly once acclimated Mature skin (50+) Needs: More aggressive anti-aging May have thinner, more fragile skin Strategy: Build up to potent retinol (0.5-1%) gradually Use multiple peptide types (signal + copper + neurotransmitter) Apply peptides AM and PM Retinol PM only Rich, nourishing moisturizers Injectable peptides vs topical peptides with retinol Beyond topical skincare, some people use injectable peptides for anti-aging
